- Evaluation of cytopathologic diagnosis of lung carcinoma.
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In Ae Park, Eui Keun Ham
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Korean J Cytopathol. 1991;2(1):20-27.
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- In order to evaluate the role of cytopathologic diagnosis of sputum, bronchial washing and bronchial brushing in the diagnosis of lung cancer, we performed this study. The patients included in this study had undergone sputum, bronchial washing and brushing cytology over the 20-month period of 1985 through 1987.
The total number of specimens was 5,495 of 2,242 patients, including 4,830 sputa and 665 bronchial washing and brushings. The average number of sputa and bronchial washings and brushings per case was 2.4 and 1.2 respectively. Among them, about 10% were unsatisfactory specimen, and three-fourths were negative specimens. In sputum cytology, the diagnosis of "atypical cells" was given to 3%, "suspicious for malignancy" was given to 1 %, and "malignancy" was given to 13%. In bronchial washing and brushing cytology, the diagnosis of "atypical cells", "suspicious for malignancy" and malignancy" was given to 6%, 3%, and 20% respectively. The cases diagnosed as "atypical cells" in cytology were actually malignancy in 95% and 84.8% of sputum and bronchial washing and brushings respectively, and the "suspicious for malignancy" were actually malignancy in 100% in both methods. The detection rates of malignancy were 50.4% and 55.2% in sputum and bronchial washing and brushing respectively, and the specificity was 100% in both methods. The accuracy of cell typing was 92% in sputum and 89.7% in bronchial washing and brushing.
- Carcinoma in situ of the urinary bladder in bladder washing cytology.
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Doo Hyun Chung, In Ae Park, Eui Keun Ham
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Korean J Cytopathol. 1991;2(1):51-55.
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- The diagnosis of carcinoma in situ of urinary bladder is difficult in that the symptoms and cystoscopic findings are nonspecific. The cytology of urine could be helpful for diagnosis of carcinoma in situ of urinary bladder.
We present a case of bladder washing cytology of carcinoma in situ.
A 54 year old man presented with dysuria for 1 year.
Cystoscopic findings revealed multifocal reddish trabeculated lesions. The bladder washing cytology revealed rather uniform tumor cells which were singly scattered or forming syncytium in the clean background. The nuclei were round to oval with inconspicious nucleoli. The cystoscopic biopsy revealed typical histologic features of carcinoma in situ of urinary bladder.
- Fine Needle Aspiration Cytology of the Mediastinal Lesions.
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In Ae Park, Eui Keun Ham
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Korean J Cytopathol. 1990;1(1):43-50.
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- The authors report 16 cases of mediastinal fine-needle aspiration cytology from Jan. 1985 to Mar. 1988 at the Seoul National University Hospital.
Among them, diagnostic materal were obtained in fifteen cases, establishing the diagnosis of 7 thymomas, 2 germinomas, 2 neurogenic tumosr, 1 lymphoma, and 3 meastatic carcinomas.
The 9 cytologic diagnoses could be confirmed by histologic examination in 8 patients and by another cytologic method in one patient, allowing concordance rate of 77%.
- A histopathologic Study of 35 congenital Neck Cysts
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Geung Hwan Ahn, Je Geun Chi, Jae Young Lee, Eui Keun Ham, Sang Kook Lee
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Korean J Cytopathol. 1968;2(2):135-141.
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- A histopathologic observation of 35 congenital cysts of the neck (19 branchial cysts and 16 thyroglossal duct cysts) obtained during a period of 10 years, 1958 to 1967, at the department of pathology, College of Medicine, Seoul National University, is presented.
The sex ratio of male and female of branchial cyst was 8: 11.
The age distribution of branchial cysts showed the highest frequency in the decade of 21-30 (36.9%) and also considerably high frequencies in the decade of 11-20(31.5%). Branchial cysts were usually located along theanterior border of the sternocleidomastoid muscle and above or below the sternocleidomastoid muscle in the lateral aspect of the neck.
Microscopically there observed stratified squamous epithelial linings in 68.4% of the total cases and lymphoid tissues in 89.5%, among which sinusoids are noted in 78.9% of the cases.
The sex ratio of male and female of thyroglossal duct cyst was 3:5. The age distribution of the thyroglossal duct cyst showed the highest frequency in the decade of 0-10(31.3%) and also considerably high frequency in the decade 21-30 (25.0%).
The thyroglossal duct cysts were usually located in the median portion of the anterior aspect of the neck.
Microscopical1y stratified squamous linings are observed in 37.5% of the cases and pseudostratified ciliated columnar in 31.3%. No lymphoid tissues are reserved and there are noted normal thyroid follicles in the cyst wall in 37.5% of the cases.
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